For a full publication list, click on:
PubMed, Scopus, Google Scholar or Orcid

Selected Publications (Original research articles)

Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Kocaturk NM, Peker N, Eberhart K, Akkoc Y, Deveci G, Dengjel J, Gozuacik D*. Cell Death and Disease. 2022 Nov 10;13(11):947. doi: 10.1038/s41419-022-05339-x. (SCI, Impact Factor: 9.68).

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis. Akkoc Y, Dalci K’, Karakas HE’, Erbil-Bilir S, Yalav O, Sakman G, Celik F, Arikan S, Zeybek U, Ergin M, Akkiz H, Dilege E, Dengjel J, Dogan-Ekici AI, Gozuacik D*. Autophagy. 2023 Jan;19(1):306-323. doi: 10.1080/15548627.2022.2090693. (SCI, Impact Factor: 13.39).

A novel ATG5 interaction with Ku70 potentiates DNA repair upon genotoxic stress. Demirbag-Sarikaya S’, Akkoc Y’, Turgut S, Erbil-Bilir S, Kocaturk NM, Dengjel J, Gozuacik D*. Scientific Reports. 2022 May 17;12(1):8134. doi: 10.1038/s41598-022-11704-9. (SCI, Impact Factor: 4.99).

Treatment of breast cancer with autophagy inhibitory microRNAs carried by AGO2-conjugated nanoparticles. Unal O’, Akkoc Y’, Kocak M, Nalbat E, Dogan-Ekici AI, Yagci Acar H*, Gozuacik D*. Journal of Nanobiotechnology. 2020 Apr 28;18(1):65. doi: 10.1186/s12951-020-00615-4. (SCI, Impact Factor: 9.42).

MITF/MIR211 axis is a novel autophagy amplifier system during cellular stress. Ozturk DG, Kocak M, Akcay A, Kinoglu K, Kara E, Buyuk Y, Kazan H and Gozuacik D*. Autophagy, 2019 Mar;15(3):375-390. doi: 10.1080/15548627.2018.1531197. (SCI, Impact Factor: 13.39).

A microfluidic chip for screening individual cancer cells via eavesdropping on autophagy inducing crosstalk in the stroma niche. Karakas HE’, Kim JY’, Park J, Oh JM, Choi Y, Gozuacik D*, Cho YK*. Scientific Reports, 2017. 7(1):2050. doi: 10.1038/s41598-017-02172-7. (SCI, Impact Factor: 4.99).

RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. Erbil S, Oral O, Mitou G, Cenk Kig, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik D*. The Journal of Biological Chemistry, 2016. 291(32):16753-65. doi: 10.1074/jbc.M115.708081. (SCI, Impact Factor: 5.48).

MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5. Tekirdag AK’, Korkmaz G’, Ozturk DG, Agami R, Gozuacik D*. Autophagy, 2013 Mar;9(3):374-85. doi: 10.4161/auto.23117. (SCI, Impact Factor: 13.39).

Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. Oral O’, Oz-Arslan D’, Itah Z, Naghavi A, Deveci R, Karacali S, Gozuacik D*. Apoptosis, 2012 Aug; 17(8):810-20. doi: 10.1007/s10495-012-0735-0. (SCI, Impact Factor: 5.56).

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. Korkmaz G, le Sage C, Tekirdag AK, Agami R, Gozuacik D*. Autophagy, 2012 February; 8 (2): 165-176. doi: 10.4161/auto.8.2.18351. (SCI, Impact Factor: 13.39).

Selected Publications (Review articles)

Autophagy and Cancer Dormancy. Akkoc Y, Peker N, Akcay A, Gozuacik D*. Frontiers in Oncology. 2021 Mar 19; 11:627023. doi: 10.3389/fonc.2021.627023. (SCI, Impact Factor: 5.74).

MicroRNAs as major regulators of the autophagy pathway. Akkoc Y, Gozuacik D*. Biochimica Biophysica Acta - Molecular Cell Research. 2020 May;1867(5):118662. doi: 10.1016/j.bbamcr.2020.118662. (SCI, Impact Factor: 5.01).

Autophagy as a Cellular Stress Response Mechanism in the Nervous System. Peker N, Gozuacik D*. Journal of Molecular Biology. 2020 Apr 3;432(8):2560-2588. doi: 10.1016/j.jmb.2020.01.017. (SCI, Impact Factor: 6.15).

Autophagy as a molecular target for cancer treatment. Kocaturk NM, Akkoc Y, Kig C, Bayraktar O, Gozuacik D, Kutlu O*. European Journal of Pharmaceutical Sciences. 2019 Jun 15;134:116-137. doi: 10.1016/j.ejps.2019.04.011. (SCI, Impact Factor: 5.11).

Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System. Kocaturk NM, Gozuacik D*. Frontiers in Cell and Developmental Biology. 2018 Oct 2;6:128. doi: 10.3389/fcell.2018.00128. (SCI, Impact Factor: 6.08).

Autophagy-Regulating microRNAs and Cancer. Gozuacik D*, Akkoc Y, Ozturk DG, Kocak M. Frontiers in Oncology. 2017 Apr 18;7:65. doi: 10.3389/fonc.2017.00065. (SCI, Impact Factor: 5.74).

Selected Publications (Book chapters)

Otofaji ve Kanser. Gozuacik D*, Karakaş HE, Akkoç Y, Özata B. In the book: Kanser Moleküler Biyolojisi (In Turkish). Yusuf Baran (Ed.). Hipokrat Publishing, 2022. Stok Kodu: 9786257399050

Autophagy as a physiological response of the body to starvation. Erbil-Bilir S, Gozuacik D, Kutlu O*. In the book: Handbook of Famine, Starvation, and Nutrient Deprivation: From Biology to Policy. Victor R. Preedy and Vinood B. Patel (Eds.). Springer Publishing, 2017. ISBN-13: 978-3319553863.

Cell death and autophagy: A historical perspective. Gozuacik D* and Kig C. In the book: 20 Years of Cell Death. Richard Lockshin and Zahra Zakeri (Eds.). An Anniversary Publication of the International Cell Death Society (ICDS), 2015. ASIN: B00Z7VKCU0.

Autophagy in health and disease. Arachiche A and Gozuacik D*. In the book: Toxicity and autophagy in neurodegenerative disorders. Jose Manuel Fuentes (Ed.). Springer Publishing. 2015. ISBN: 978-3-319-13938-8.

Regulation of autophagy by miRNAs. Tekirdag KA, Ozturk DG, Gozuacik D*. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2015. ISBN: 9780128010327.

Induction of autophagic cell death by anticancer agents. Eberhart K, Oral O, Gozuacik D*. pp 179-202. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2013. ISBN: 9780124055308.

‘, Equal contribution. *, Corresponding author.